{"id":2484,"date":"2004-12-01T09:05:27","date_gmt":"2004-12-01T08:05:27","guid":{"rendered":"https:\/\/staging.biofizika.hr\/?p=2484"},"modified":"2025-07-13T15:41:00","modified_gmt":"2025-07-13T13:41:00","slug":"prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture","status":"publish","type":"post","link":"https:\/\/biofizika.hr\/en\/2004\/12\/01\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\/","title":{"rendered":"SPLIT PREDICTOR From amino acid sequence to secondary structure"},"content":{"rendered":"

Lecturer<\/h3>\n\n\n\n

LARISA ZORANIC, M.Sc.
Faculty of Natural Sciences and Education, Split<\/p>\n\n\n\n

Date and time<\/h3>\n\n\n\n

Monday, December 13, 2004 at 4:00 PM<\/p>\n\n\n\n

Location<\/h3>\n\n\n\n

Lecture Hall, Wing I, Ru\u0111er Bo\u0161kovi\u0107 Institute, Bijeni\u010dka 54, Zagreb<\/p>\n\n\n\n

Abstract<\/h3>\n\n\n\n

How to predict the three-dimensional structure of a protein, if only the amino acid sequence is known, is one of the greatest scientific challenges of today. Information technology, i.e. bioinformatics, has developed tools that could lead to a solution to this problem. However, difficulties such as a large amount of unclassified biological data together with a small number of crystallographically known 3D structures limit bioinformatics research and emphasize the need for strict control of the obtained results. This is especially true for integral membrane proteins whose great medical and biological importance is disproportionate to the small number of known three-dimensional structures. For example, the first Croatian bioinformatics server SPLIT (http:\/\/split.pmfst.hr\/split\/<\/a>) will describe the way of developing bioinformatics tools. The SPLIT program predicts transmembrane domains of integral membrane proteins by modeling hydrophobicity or statistical propensities of amino acid residues. The basis of the prediction is the conformational profiles calculated via propensity functions. Comparison of algorithms with already recognized bioinformatics tools showed that the SPLIT program is at the very top of the group of best predictors of transmembrane domains in the world.<\/p>","protected":false},"excerpt":{"rendered":"

Lecturer: LARISA ZORANI\u0106, M.Sc. Faculty of Natural Sciences and Mathematics and Educational Sciences, Split Date and time: Monday, December 13, 2004 at 4:00 PM\u2026<\/p>","protected":false},"author":4,"featured_media":2478,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"iawp_total_views":3,"footnotes":""},"categories":[15],"tags":[],"class_list":["post-2484","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-seminari"],"yoast_head":"\nPREDIKTOR SPLIT Od aminokiselinskog slijeda do sekundarne strukture - Biofizika<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/biofizika.hr\/en\/2004\/12\/01\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PREDIKTOR SPLIT Od aminokiselinskog slijeda do sekundarne strukture - Biofizika\" \/>\n<meta property=\"og:description\" content=\"Predava\u010d mr.sc. LARISA ZORANI\u0106Fakultet prirodoslovno-matemati\u010dkih znanosti i odgojnih podru\u010dja, Split Datum i vrijeme Ponedjeljak, 13. prosinca 2004. u 16:00 sati...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/biofizika.hr\/en\/2004\/12\/01\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\/\" \/>\n<meta property=\"og:site_name\" content=\"Biofizika\" \/>\n<meta property=\"article:published_time\" content=\"2004-12-01T08:05:27+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-13T13:41:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/biofizika.hr\/wp-content\/uploads\/2021\/04\/pexels-fox-1595385-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jasmina\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jasmina\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/\"},\"author\":{\"name\":\"Jasmina\",\"@id\":\"https:\\\/\\\/biofizika.hr\\\/en\\\/#\\\/schema\\\/person\\\/2086215e6e24966c1e98f57493f1da51\"},\"headline\":\"PREDIKTOR SPLIT Od aminokiselinskog slijeda do sekundarne strukture\",\"datePublished\":\"2004-12-01T08:05:27+00:00\",\"dateModified\":\"2025-07-13T13:41:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/\"},\"wordCount\":215,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/biofizika.hr\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/biofizika.hr\\\/wp-content\\\/uploads\\\/2021\\\/04\\\/pexels-fox-1595385-scaled.jpg\",\"articleSection\":[\"Seminari\"],\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/\",\"url\":\"https:\\\/\\\/biofizika.hr\\\/2004\\\/12\\\/01\\\/prediktor-split-od-aminokiselinskog-slijeda-do-sekundarne-strukture\\\/\",\"name\":\"PREDIKTOR SPLIT Od aminokiselinskog slijeda do sekundarne strukture - 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