Links – Hrvatsko biofizičko društvo

Croatian biophysical society is an active member of international organizations that have the purpose to promote biophysics.

Repeatability, precision, and accuracy of the enthalpies and Gibbs energies of a protein–ligand binding reaction measured by isothermal titration calorimetry 08/12/2018
Abstract In rational drug design, it is important to determine accurately and with high precision the binding constant (the affinity or the change in Gibbs energy, ∆G), the change in enthalpy (ΔH), and the entropy change upon small molecule drug binding to a disease-related target protein. These thermodynamic parameters of the protein–ligand association reaction are […]
Another interpretation of the Goldman–Hodgkin–Katz equation based on Ling’s adsorption theory 01/12/2018
Abstract According to standard membrane theory, the generation of membrane potential is attributed to transmembrane ion transport. However, there have been a number of reports of membrane behavior in conflict with the membrane theory of cellular potential. Putting aside the membrane theory, we scrutinized the generation mechanism of membrane potential from the view of the […]
Affinity determination of biomolecules: a kinetic model for the analysis of pre-equilibrium titration curves 01/12/2018
Abstract Equilibrium titration curves have been used to determine the affinity of biomolecules using a variety of platforms and technologies. Such measurements, however, are experimentally limited by the time that is needed for the system to reach the equilibrium, which may exceed the time during which the studied biomolecules are stable. We propose here a […]